Mots-clés: adénocarcinome-pathologie, lymphome à cellules B, lymphome à petites cellules, . centroblaste et de cellule plasmocytaire (H et E, X 90). La maladie des chaînes alpha et le lymphome méditerranéen (figs. le lymphome méditerranéen, caractérisé par une infiltration plasmocytaire maligne, . Si une prolifération cutanée lympho-plasmocytaire monoclonale et monotypique suggère prioritairement un lymphome cutané de la zone marginale (LCZM) ou.

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Case report

Transformation progressive des centres germinatifs. For each condition, the criteria allowing plasnocytaire propose the right diagnosis are discussed. Journal page Archives Contents list. Vergier fM. Le Pathologiste, Elsevier Masson, Paris Mendes eB.

Two cases of proliferation of monoclonal and monotypic lymphocytes and plasma cells corresponding to acrodermatitis chronica atrophicans.

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Lymphome lymphoplasmocytaire

Further, it is recommended that antibiotics be considered in CMZL before undertaking systemic therapy. Difficulties in the interpretation of histologic lesions in lymph node pathology betwen lymphoma and reactive or inflammatory modifications. You can move this window by clicking on the headline. The files of two patients were submitted for discussion at the regional multidisciplinary staff meeting on cutaneous lymphomas after review of the skin biopsies led to a diagnosis of plasmacytoma and CMZL on the basis of infiltrate containing abundant plasma cells.

Contact Help Who are we? The classic histological appearance of the tertiary phase of early-stage Lyme’s disease shows perivascular and periadnexal infiltrate comprising lymphocytes and plasma cells.

Lymphome lymphoplasmocytaire – Société canadienne du cancer

Access to the PDF text. Difficulties ;lasmocytaire interpret the histology may be due to various artefacts, which should be well known by the pathologist, and which are presented in the first part of this article.

The monoclonal and monotypic nature of skin proliferation points above all to CMZL or plasmacytoma. While a dermal proliferation of monotypic monoclonal lymphocytes and plasma cells suggests above all cutaneous plqsmocytaire zone lymphoma CMZL or plasmacytoma, it may also correspond to a Borrelia infection of which the clinic picture is evocative, as demonstrated in the cases presented herein.


Access to the text HTML. The infiltrates of both patients showed a kappa monotypic light chain and cutaneous B-cell clones were detected.

You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted. The greatest difficulties in the interpretation of nodal lesions are found in the distinction between reactive inflammatory and neoplastic proliferations. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used plasnocytaire stored, be corrected, clarified, updated or deleted.

Lyme, BorreliaPlasmacytoma, Marginal zone lymphoma, Acrodermatitis chronica atrophicans, Monoclonality. If you are a subscriber, please sign in ‘My Account’ at the top right of the screen. A link between Borrelia infection and cutaneous lymphomas has long been thought to lymhome. If you want to subscribe to this journal, see our rates You can purchase this item in Pay Per View: However, the clinical features, with monomelic maculopapular rash, were evocative primarily of Borrelia infection.

Coindre cP.