LAKTAT DEHIDROGENASE PDF

Lactate dehydrogenase is an enzyme that helps turn sugar into energy for your cells. High LDH levels could indicate cell damage. Laktat dehydrogenase (LD. LDH): enzim intraseluler yang terdapat pada hampir semua sel yang bermetabolisme Merupakan enzim pemberi ion hydrogen. GAMMA glutamyl Transpeptidase dan laktat dehidrogenase. RT. Rini Teke. Updated 29 May Transcript. INTERPRETASI DATA KLINIS.

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To correlate the severity of the disease, maternal and perinatal outcome with Lactic Dehydrogenase LDH levels in serum in patients of preeclampsia and degidrogenase. A prospective comparative study was conducted in the department of Obstetrics and Gynecology in the collaboration with department of Pathology, CSM Medical University, Lucknow.

Out of women studied, 39 were normal pregnant women, 35 were of mild preeclampsia, 36 of severe preeclampsia and 36 of eclampsia. High serum LDH levels correlate well with the severity of the disease and poor outcomes in patients of preeclampsia and eclampsia. These are multisystem disorders and lead to a lot of cellular death. LDH is an intracellular enzyme and its level is increased in these women due to cellular death.

So, serum LDH levels can be used to assess the extent of cellular death and thereby the severity of disease in this group of women. This can be further used as help in making dehidrogemase, regarding the management strategies to improve the maternal lakfat fetal outcome. Pregnant women were enrolled in this study in the third trimester of pregnancy and divided into following groups:. All women were followed until delivery and early postpartum period and babies till early neonatal period.

Total patients were studied, out of which 39 Out of these cases 35 Only two patients 5.

The mean Lqktat level calculated as Out of 36 cases of severe preeclampsia, 21 cases The mean LDH levels were In eclampsia group, majority of patients i. While only 7 The mean LDH level in this group was laktaat Various parameters of peri-natal outcomes in respect to LDH levels, have been studied.

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The mean gestational age at the time of delivery was The mean weight in the third group i. When LDH levels were normal 56 cases47 In this group 4 In the third group where LDH levels were markedly elevated i. In the third group i. One case each of abruption placentae, HELLP syndrome with RF, metabolic encephalopathy, pulmonary embolism, pulmonary edema and renal failure and two cases of cerebrovascular accident were present.

In the present study majority of the patients belonged to younger age group and were nulliparous.

Lactic Dehydrogenase: A Biochemical Marker for Preeclampsia–Eclampsia

This finding was dehidrogenawe observed by Qublan et al. This indicates increase in preterm deliveries in patients with higher LDH levels. The association of low birth weight of infants with increase in serum LDH levels was suggested by He et al.

This was in contrary to Qublan et al. This could partially be due to higher incidence of premature births in this group.

Increase in the incidence of perinatal deaths was observed by Qublan et al. Intrauterine fetal death was seen in 4. Neonatal deaths were reported in It was noted that in early onset severe preeclampsia, LDH levels before delivery were significantly higher in the abruption group Odendaal et al. Higher serum LDH levels were associated with increased incidence of maternal complications like abruption placenta, renal failure HELLP syndrome, cerebrovascular accidents etc.

Maternal mortality was To conclude LDH levels have significant association with various maternal and fetal outcomes in patients of preeclampsia and eclampsia.

Lactic Dehydrogenase: A Biochemical Marker for Preeclampsia–Eclampsia

National Center for Biotechnology InformationU. J Obstet Gynaecol India. Published online Jan 4. Natuand Mohan Shaili. Author information Article notes Copyright and License information Disclaimer.

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Received Jul 27; Accepted Aug 5. This article has been cited by other articles in PMC.

Abstract Objectives To correlate the severity of the disease, maternal and perinatal outcome with Lactic Dehydrogenase LDH levels in serum in patients of preeclampsia and eclampsia.

Conclusion High serum LDH levels correlate well with the severity of the disease and poor outcomes in patients of preeclampsia and eclampsia. Lactic, Dehydrogenase, Preeclampsia, Eclampsia, Maternal outcome.

The aims of the llaktat study are To compare serum LDH levels in the normal pregnant women and in women with preeclampsia and eclampsia in ante-partum period.

Pregnant women were enrolled in this study in the third trimester of pregnancy and divided into following groups: Group 1—healthy normal pregnant women controls. Group-2—patients of preeclampsia and eclampsia subjects. This was further subdivided into following subgroups Mild preeclampsia.

Lactate Dehydrogenase Test

Results Total patients were studied, out of which 39 Open in a separate window. Discussion In the present study majority of the patients belonged to younger age group and were nulliparous. LDH as biochemical marker of adverse pregnancy outcome in severe preeclampsia. Increased concentrations of lactate dehydrogenase in pregnancy with preeclampsia; a predictor for birth of small for gestational age infants.

Early risk assessment of severe preeclampsia: Am J Obstet Gynecol.

Severe preeclampsia with fulminant and extreme elevation of aspartate aminotransferase and lactate dehydrogenase levels. Factors that influence dehifrogenase, and mortality in severe preeclampsia, eclampsia and HELLP syndrome. Expectant management of early onset, severe preeclampsia perinatal outcome. Support Center Support Center. Please review our privacy policy.