Aditya Choudhary et al. Froin Syndrome. 1Aditya Choudhary, 2Manoj K Goyal, 3Manish Modi, 4Kanchan K Mukherjee, 5Chirag K Ahuja, 6Vivek Lal. Georges Froin (–), a French physician practising at the turn of the century, was the first to describe the xanthochromia and marked coagulation of. Froin Syndrome is characterized with xanthochromic CSF, high CSF protein content, complete blockage of CSF circulation. We reported our case of Froin.

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Many trials, including rotating the needle, repeated tapping, position change, and aspiration, should be attempted before spinal drug administration [ 2 ]. Subarachnoid space was accessed at L intervertebral space through a 22G spinal needle under sterile conditions. The patient’s Synxrome showed high protein 3, His lumbar puncture revealed a yellow cerebrospinal fluid CSF that became instantly gelatinous Figure 1A. Guidelines Upcoming Syndrom Issues.

Similar to Miraz’s case of Pseudo-Froin’s syndrome, with a large bulging disc in the lumbar spine, this case showed xanthochromia, high protein content, marked coagulation of the CSF, and dry tapping without spinal meningitis, malignancy, or abscess.

Retrieved from ” https: Syndome analysis of xanthochromia is recommended for distinction between a traumatic spinal tap and a true intracranial bleed in cases when a yellow color of the CSF syndeome observed. Chest CT showed a left lower lobe lung mass. The first time spinal anesthesia was performed, the CSF flow was very scanty and sticky, and the color was dark yellow.


No motor or sensory abnormalities were found in the upper chest or upper extremities.

Orphaned articles from January All orphaned articles Infobox medical condition new All stub articles. Agri and Aquaculture Journals Dr. Ependymoma of the cervical spinecompletely obscurating the spinal canal. In the case discussed here, the patient had froinn from year paraplegia with newly-developed urinary bladder cancer and showed abnormal CSF characteristics at spinal anesthesia.

Nonne-Froin sign | QJM: An International Journal of Medicine | Oxford Academic

Close mobile search navigation Article navigation. The cause of the high protein content of the spinal fluid is meningeal irritation and inflammation.

fron A clinical test formerly used for evaluation of spinal stenosis is Queckenstedt’s maneuver. More on this topic Harlequin nail. Therefore, a tumor of the spine was a suspicious cause of the xanthochromia, and CSF evaluation was performed immediately after CSF collection.

His paper was published in Gazette des hopitaux in [ 1 ].

Pseudo-Froin’s syndrome on MRI”. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License http: Picture is taken immediately after the CSF collection. No specific problems such as headache, reflex tachycardia, or sweating were observed in the perioperative period. Comparative values of CSF-cholesterol and CSF-triglycerides along with other biochemical parameters in neurological disorders.

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The patient had suffered from paraplegia for 20 years because of a thoracic spine burst fracture T and dislocation. Report from EFNS task force. Dry tap and spinal anesthesia. Case Report Open Access.


Pseudo-Froin’s syndrome, xanthochromia with high protein level of cerebrospinal fluid

Spinal drug administration was done after CSF confirmation by aspiration. Oxford University Press is a department of the University of Oxford.

Interruption of the spinal canal and stagnation of the CSF by a neoplastic mass or herniated disc contribute to the sequestered CSF circulation and the high protein content of the CSF. This condition was considered to be investigated and anesthesia was abandoned.

Incidental Finding of Froin Syndrome during Spinal Anesthesia in a 72-Year-Old Patient

Froin’s syndrome is characterized by marked cerebrospinal fluid CSF xanthochromia yellow discoloration of the CSF and hypercoagulability due to increased protein content.

Pseudo-Froin’s syndrome has been described as stagnation of the CSF distal to a spinal block due to spinal disc bulging or tumors [ 1 ]. CSF syndroe results of the patient were consistent with Froin syndrome. For Permissions, please email: Yellow discoloration and coagulation of the CSF was first described in meningitis by Georges Froin in syndrom in spinal tumours by Max Nonne, 3 hence the name Nonne-Froin sign.