Request PDF on ResearchGate | Dermatitis granulomatosa intersticial con artritis | —Interstitial granulomatous dermatitis with arthritis is a systemic disease. La dermatitis granulomatosa intersticial con artritis es una enfermedad sistémica que afecta a la piel y al sistema musculosquelético. Esta nueva entidad se. Summary. An Orphanet summary for this disease is currently under development. However, other data related to the disease are accessible from the Additional.

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Dermatitis granulomatosa intersticial en placas con artritis en una adolescente: Informe de un caso

Summary and related texts. Interstitial granulomatous dermatitis associated with the use of tumor necrosis factor alpha inhibitors. Interstitial granulomatous dermatitis in rheumatoid arthritis responsive to etanercept.

Detail of infiltrate with histiocytes, lymphocytes, eosinophils and neutrophils amid thickened collagen. IGD may also be the heralding symptom for lymphoproliferative diseases, solid organ cancer, or represent an adverse drug reaction, including to the newer biologic agents. It has been reported in association with several drugs, lymphoproliferative diseases and branulomatosa disorders, such as rheumatoid arthritis, systemic lupus erythematosus and vasculitis, but association with autoimmune thyroiditis is rare.

Autoimmune thyroiditis presenting as interstitial granulomatous dermatitis

March Pages Accentuation of the process in the reticular dermis is a characteristic feature, although abnormalities can involve the full thickness of the dermis or the superficial hypodermis. Interstitial granulomatous dermatitis with arthritis is a rare rheumatologic disease characterized by the occurrence of inflammatory arthritis in association with large, erythematous, symmetrical cutaneous lesions ranging from typical, but infrequent, cord-like lesions on the flanks to more common violaceous plaques on the trunk and limbs featuring a typical histologic infiltrate mainly constituted of histiocytes.


Normalization of thyroid function and high-potency topical corticosteroids provided only transitory improvement of the dermatosis. Journal List An Bras Dermatol v. Topical corticosteroids appear to be only moderately effective, but are still a first line treatment, especially in patients with localized disease.

This new entity is characterized by the formation of cords in a linear or arcuate arrangement, although a wide range of clinical presentations has been described. Please review our privacy policy.

Optimal therapy for this condition is yet to be established, but topical corticosteroids have been a mainstay of treatment. Check this box if you wish to receive a copy of your message. Julio Bassas aPablo Umbert b. Relapsing polychondritis, interstitial granulomatous dermatitis and antiphospholipid syndrome: You can change the settings or obtain more information by clicking here.

Granulomatous dermatitis

We describe a middle aged woman with rheumatoid arthritis of difficult management and cutaneous lesions compatible with IGDA. Interstitial granulomatous dermatitis with cutaneous cords and arthritis: She was medicated with high potency topical corticosteroid and evaluated by an endocrinologist who prescribed levothyroxine.


Self-skin examination New smartphone apps to check your skin Learn more Sponsored content. J Am Acad Dermatol.

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Interstitial granulomatous dermatitis is a rare skin disorder in which there dermayitis a particular pattern of granulomatous inflammation. Interstitial granulomatous drug reaction is diagnosed by skin biopsy.

Dense inflammatory infiltrate in interstitial thickened collagen. Its physiopathology is uncertain, however the association with autoimmune diseases and vasculitides suggests a mechanism mediated by immunocomplexes.