Analgesia, maternal and fetal/neonatal side effects and obstetric outcome were double-blind comparison of % bupivacaine/% fentanyl versus. Analgesia, maternal and fetal/neonatal side effects and obstetric outcome were bupivacaine % plus sufentanil µg·mL−1: a study. Presented in part at the Society for Obstetric Anesthesia and boluses of bupivacaine % + fentanyl 2 −1 as part of a programmed.

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These findings are supported by a meta-analysis of impact studies in which a dramatic increase in the epidural rate had no impact on operative delivery rates. Randomised controlled comparison of epidural bupivacaine versus pethidine for analgesia in labour. No clear advantages have been demonstrated obstetic compared with midwife administered low dose top-ups.

However, monitoring of the fetus remains important. The total dose of LA and opioid is actually increased when compared with low dose top-ups. It has a rapid onset and lasts for 1—2 h when given as a bolus. Greater lipid solubility theoretically means that diamorphine rapidly penetrates the cord, leaving little drug available for cephalad spread.

Continuous epidural infusion of 0.

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As a result of this, considerable research has been performed and findings have led to changes in practice. This included 10 studies and patients of mixed parity. However, its use is associated with sedation and hypotension and it is not widely used in obstetrics. Other drugs that have been investigated include epinephrine, ketamine, neostigmine, remifentanil and midazolam. Combined spinal epidural versus epidural analgesia in labour.

Epidural analgesia in labour | BJA Education | Oxford Academic

Continuous infusion epidural analgesia during Labour: Though randomized controlled trials RCT are considered the gold standard for research, in labour they can be difficult obstetrif blind and therefore, there is potential for observer bias. The needle-through-needle technique may have a longer learning curve and a higher incidence of technical failure compared with single-shot spinals or epidurals.


Fluid preloading has been shown not only to be ineffective in preventing the modest reductions in blood pressure associated with low dose epidurals, but also associated with a decrease in uterine contractions, which 0.6025 last up to 1 h. Key points Compared with other methods, epidural analgesia provides superior analgesia in labour. Epidurals do not increase caesarean section rates or the incidence of back pain.

Suggested advantages are very rapid onset of analgesia with a similar time to set up and perform the block and high maternal satisfaction rates. They do not obsyetric as long as traditional top-ups and may be inadequate for instrumental vaginal delivery. Uterine activity appears to be unaffected by induction of regional block.

Forty parturient admitted to Chennai Medical College and Hospital, Trichy, for vaginal delivery and who were in active labor was given 8 ml of 0. When compared with conventional epidural analgesia, the total LA dose is reduced with CSE and patients have less motor block over the course of labour, allowing them to ambulate if desired. Effect of pH-adjustment of bupivacaine on onset and duration of epidural analgesia in parturient. Several recent large RCTs comparing epidural with non-epidural analgesia during labour have shown that epidural analgesia does not increase the caesarean ostetric rate, whether attributable to dystocia or fetal distress.

In theory, LDI should decrease anaesthetic workload, provide more constant analgesia and better haemodynamic stability and sterility. A clinical study of the effectiveness of lbstetric epidural labour analgesia for vaginal delivery with 0. The mode of delivery and the Apgar scores of the neonates at 1 and 5 minutes were comparable.


Bearing in mind the above, how can we optimize labour epidural analgesia to ensure superior analgesia while minimizing the effects on labour? The low-dose regimen provides effective, rapid onset analgesia and high maternal satisfaction rates when compared with traditional top-ups. On the other hand, CSE may reduce accidental dural puncture rates. Comparison of ropivacaine 0. Article Tools Print this article. The main concern is that this pyrexia leads to unnecessary investigations for mother and baby, and a greater use of antibiotics.

Presumably this is the result of the preservation of muscle tone and the bearing down reflex. Sufentanil is used extensively in the US. In addition, there are equipment and cost issues to consider.

Since epidural analgesia was introduced four decades ago for pain relief in labour, controversy has persisted about its effect on the labour process. We have a duty to provide optimal analgesia during labour. Fentanyl is perhaps the most commonly used opioid in the UK. The side effects were mild sedation and in the parturient who received fentanyl. These are the traditional intermittent boluses of LA, typically bupivacaine 0.

It provides effective analgesia and high maternal satisfaction rates, as mothers feel they are in control of their analgesia.